- Original Article
- Effect of endothelin receptor blockade on monocrotaline-induced pulmonary hypertension in rats
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Kyoung Ah Lim, Jung Yun Shim, Sang Ho Cho, Kwan Chang Kim, Jae Jin Han, Young Mi Hong
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Clin Exp Pediatr. 2009;52(6):689-695. Published online June 15, 2009
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Purpose : To examine the effect of bosentan, a dual endothelin receptor (ER) antagonist, on the development of monocrotaline (MCT)-induced pulmonary hypertension in rats by especially focusing on the pulmonary vascular morphology changes.
Methods : Sprague-Dawley rats were treated as follows: controls received a subcutaneous saline injection, MCT-treated rats received a subcutaneous MCT injection, and bosentan-treated rats received a MCT... |
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- Case Report
- Cushing’s Syndrome in Infancy
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Pyung Kil Kim, Ki Sub Chung, Duk Jin Yun, Sang Hyon Suh, Sang Ho Cho
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Clin Exp Pediatr. 1969;12(11):639-648. Published online November 30, 1969
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There are little reports on the Cushing’s syndrome in children, especially in infancy in Korea. We have found recently a case of Cushing’s syndrome in infancy arising from a female infant. She has been complained from eleven month of age with general obesity including buffalo hump, excessive weight: gain, hirsutism and polyphgagia. Laboratory tests revealed that no thymic shadow in... |
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